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Genetics

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  1. 0 reviews 0 5 5 5 out of 5 stars 5/5
    6.7 hrs • 4/15/2014 • Unabridged

    Combine the counterintuitive nature of Freakonomics with the fascinating medical tales of Oliver Sacks or Jerome Groopman and you’ll have Inheritance—the new book by award-winning geneticist and New York Times bestselling author Sharon Moalem that reveals how genetic breakthroughs are transforming our understanding of the world … and ourselves. Conventional wisdom dictates that our genetic destiny is fixed at conception. But Inheritance shows us that the human genome is actually far more fluid, fascinating, and relevant then your ninth-grade high school biology teacher would have you believe. In this gene journey filled with authoritative, cutting-edge science based on immaculate research by one of the world’s leading authoritative voices on human genetics and health, Sharon Moalem, MD, PhD, we chart a riveting course destined to shatter all of our presuppositions about the fundamental nature of our genes. Moalem deftly brings readers to the bedside table of some of his most complicated genetic patients, and it is through these cases that we learn: how a trauma can be genetically passed down through generationsat what point during pregnancy shifted genes are passed along why a change in diet could alter genes and slow the aging process why some people are genetically born to be warriors and others worriers how insurance companies can use your genetic data to predict your (and therefore your childrens’) medical future, which can then impact the coverage decisions they make for you and your entire family, and so much more Turning the nature/nurture debate completely on its head, Inheritance will dazzle readers as they learn how to apply this compendium of groundbreaking genetic research into their daily lives and take control of their genetic destiny in a way that their parents could only have dreamed of.

    Available Formats: Download

    Inheritance

    By Sharon Moalem, MD, PhD, with Matthew D. LaPlante
    6.7 hrs • 4/15/14 • Unabridged
    0 reviews 0 5 5 5 out of 5 stars 5/5
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  2. 10.4 hrs • 1/1/2014 • Unabridged

    “In high school, I wondered whether the Jamaican Americans who made our track team so successful might carry some special speed gene from their tiny island. In college, I ran against Kenyans, and wondered whether endurance genes might have traveled with them from East Africa. At the same time, I began to notice that a training group on my team could consist of five men who run next to one another, stride for stride, day after day, and nonetheless turn out five entirely different runners. How could this be?” We all knew a star athlete in high school. The one who made it look so easy. He was the starting quarterback and shortstop; she was the all-state point guard and high-jumper. They were naturals—or were they? The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports, or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training? The truth is far messier than a simple dichotomy between nature and nurture. In the decade since the sequencing of the human genome, researchers have slowly begun to uncover how the relationship between biological endowments and a competitor’s training environment affects athleticism. Sports scientists have gradually entered the era of modern genetic research. In this controversial and engaging exploration of athletic success, Sports Illustrated senior writer David Epstein tackles the great nature versus nurture debate and traces how far science has come in solving this great riddle. He investigates the so-called ten-thousand-hour rule to uncover whether rigorous and consistent practice from a young age is the only route to athletic excellence. Along the way Epstein dispels many of our perceptions about why top athletes excel. He shows why some skills that we assume are innate, like the bullet-fast reactions of a baseball or cricket batter, are not and why other characteristics that we assume are entirely voluntary, like an athlete’s will to train, might in fact have important genetic components. This subject necessarily involves digging deep into sensitive topics like race and gender. Epstein explores controversial questions such as: Are black athletes genetically predetermined to dominate both sprinting and distance running, and are their abilities influenced by Africa’s geography? Are there genetic reasons to separate male and female athletes in competition? Should we test the genes of young children to determine if they are destined for stardom? Can genetic testing determine who is at risk of injury, brain damage, or even death on the field? Through on-the-ground reporting from below the equator and above the Arctic Circle, revealing conversations with leading scientists and Olympic champions, and interviews with athletes who have rare genetic mutations or physical traits, Epstein forces us to rethink the very nature of athleticism.

    Available Formats: CD

    The Sports Gene

    10.4 hrs • 1/1/14 • Unabridged
    CD
  3. 10.4 hrs • 8/1/2013 • Unabridged

    We all knew a star athlete in high school. The one who made it look so easy. He was the starting quarterback and shortstop; she was the all-state point guard and high-jumper. Naturals. Or were they? The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports? Or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training? The truth is far messier than a simple dichotomy between nature and nurture. In the decade since the sequencing of the human genome, researchers have slowly begun to uncover how the relationship between biological endowments and a competitor’s training environment affects athleticism. Sports scientists have gradually entered the era of modern genetic research. In this controversial and engaging exploration of athletic success, Sports Illustrated senior writer David Epstein tackles the great nature vs. nurture debate and traces how far science has come in solving this great riddle. He investigates the so-called ten-thousand-hour rule to uncover whether rigorous and consistent practice from a young age is the only route to athletic excellence. Along the way, Epstein dispels many of our perceptions about why top athletes excel. He shows why some skills that we assume are innate, like the bullet-fast reactions of a baseball or cricket batter, are not, and why other characteristics that we assume are entirely voluntary, like an athlete’s will to train, might in fact have important genetic components.

    Available Formats: Download

    The Sports Gene

    10.4 hrs • 8/1/13 • Unabridged
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  4. 6.7 hrs • 7/15/2012 • Abridged

    How did a deadly genetic disease help our ancestors survive the bubonic plagues of Europe? Was diabetes evolution's response to the last Ice Age? Will a visit to the tanning salon help bring down your cholesterol? Why do we age? Why are some people immune to HIV? Can your genes be turned on—or off? Survival of the Sickest reveals the answers to these and many other questions as it unravels the amazing connections between evolution, disease, and human health today. Joining the ranks of modern myth busters, Dr. Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria. Survival of the Sickest is filled with fascinating insights and cutting-edge research, presented in a way that is both accessible and utterly absorbing. This is a book about the interconnectedness of all life on earth—and, especially, what that means for us. Read it. You're already living it. Read by Eric Conger

    Available Formats: Download

    Survival of the Sickest

    By Sharon Moalem, MD, PhD, with Jonathan Prince
    Read by Eric Conger
    6.7 hrs • 7/15/12 • Abridged
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  5. 10.8 hrs • 7/15/2012 • Unabridged

    From New York Times bestselling author and world-renowned doctor and geneticist Francis Collins comes a book that will forever change how you think about your body, your health, and the future of medicine. A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine. Twenty-one million Americans are affected by six thousand so-called rare and orphan diseases, many of which are primarily attributable to misspelled genes. And virtually all diseases have a significant hereditary component. There have been many stories in the media about women who are testing to see if they have a mutation that leads to breast cancer or family members who are strongly at risk for heart disease or Huntington’s disease. Yet the revolution is much more fundamental than this: diabetes, heart disease, the common cancers, mental illness, asthma, arthritis, Alzheimer’s disease—all of these and other diseases are having their secrets unlocked. Now, with a simple home test that costs just a few hundred dollars, you can learn the secrets of your own DNA. Francis Collins has been at the forefront of this revolution. He was, for fifteen years, the head of the international Human Genome Project, and he now serves as the director of the National Institutes of Health. He knows better than anyone how widespread the misperceptions about human genetics are. Just in the past decade, most of what you think you know about DNA has been overturned. Much of the advice given routinely by health care providers is ill informed, so you must educate yourself about this rapidly moving area of medicine. You are guaranteed to face some surprises as well as some difficult choices about personal knowledge, treatment, and family risk. This audiobook is overwhelmingly hopeful and inspiring, offering helpful advice in every chapter. Nearly every day, diseases that were barely understood or completely misunderstood are being redefined. Families that faced common problems without hope are now discovering a new world of understanding, treatment, and prevention. You owe it to yourself to learn about your DNA: how it works, what it reveals, and the benefits and limits of this new knowledge.

    Available Formats: Download

    The Language of Life

    10.8 hrs • 7/15/12 • Unabridged
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  6. 10.4 hrs • 9/22/2010 • Unabridged

    Since the conclusion of the Human Genome Project in 2003, scientists have been racing toward a grand goal: offering individuals a decoding of their complete genetic makeup for just $1,000. As Kevin Davies reveals in this exquisitely reported account, the $1,000 genome will be a reality by 2011, and it will usher in a whole new era of personalized, genomic medicine. Capable of presenting much more advanced information than the current crop of cheek-swab services, the $1,000 complete genome raises some extraordinary possibilities. We will be able to learn if we have genes that predispose us to a host of diseases and to take a wide range of preventative measures. Drug companies may be able to create versions of drugs tailored specifically to our individual DNA. But we may also face the psychological burden of learning that we have the gene for an incurable disease, such as Parkinson’s. Acclaimed author Kevin Davies introduces the pioneers of this medical revolution and probes deeply into both the medical benefits and ethical issues of personal genetic testing, also exploring the psychological complexities of learning one’s DNA results, based on both his own experience of being tested and that of a number of others. The $1,000 Genome is an indispensable guide to the new era of personalized medicine.

    Available Formats: Download

    The $1,000 Genome

    10.4 hrs • 9/22/10 • Unabridged
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