The Philadelphia Chromosome: A Mutant Gene and the Quest to Cure Cancer at the Genetic Level
By Jessica Wapner
Read by Heather Henderson
9.73 Hours
• 05/14/2013
• Unabridged
Format:
Digital Download (In Stock)
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1 Format: Digital Download
A science journalist goes beyond the headlines to share the fascinating backstory on ground-breaking cancer research and the genetic science behind it.
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Summary
Summary
A Publishers Weekly Top 10 Book, Spring 2013
Editorial Reviews
Editorial Reviews
“The story of the Philadelphia chromosome is truly the story of modern cancer biology…Jessica Wapner stitches the whole story together with tenacity, diligence (and humor). This is a wonderful, readable, and highly informative book.” —Siddhartha Mukherjee, Pulitzer Prize–winning author of The Emperor of All Maladies
“Jessica Wapner has done two kinds of hard work gracefully: the hard work of understanding cancer genetics and the hard work of rendering that subject into human narrative, lucid explanation, and metaphor. The Philadelphia Chromosome is not just an urgently useful book. It’s also an elegant one, put together like a Swiss watch.” —David Quammen, New York Times bestselling author of Spillover
“Clearly explains how a half-century’s worth of research transformed a viciously lethal form of cancer into a chronic, treatable condition. Jessica Wapner’s meticulously researched book is both a real-life medical thriller and an engaging narrative about the history of modern cancer research.” —Seth Mnookin, New York Times bestselling author of Feeding the Monster
“The way Wapner repeatedly adds up preceding steps to build to the scientific breakthrough is masterful, making for compulsive, surprisingly emotional reading." —Scientist
“As science writer Jessica Wapner reveals in this taut, elegant study, a cascade of breakthroughs then led to success with targeted drug Gleevec, a tyrosine kinase inhibitor—and hopes for the cancer-busting potential of rational drug design in general.” —Nature
“[Wapner’s] gracefully written history skillfully combines both the science and humanity of this fascinating search for a cure for CML.” —Publishers Weekly
“An excellent book for those who want to learn more about how medical discoveries are made and those interested in recent medical history, as well as those whose lives are affected by CML.” —Library Journal
“An absorbing, complex medical detective story.” —Kirkus Reviews
“Beautifully written…a blueprint for broader healthcare change. A pivotal book.” —David B. Agus, MD, professor of medicine and engineering, University of Southern California, and author of The End of Illness
Author
Author Bio: Jessica Wapner
Jessica Wapner’s science writing has appeared in Scientific American, Slate, the New York Times, New York, Science, Nature Medicine, Ecologist, Scientist, and Psychology Today. Her writing on cancer has been published in patient-focused magazines like CR and Cure as well as Oncology Business Review. She lives in Beacon, New York, with her husband and children.
Titles by Author
Details
Details
| Available Formats : | Digital Download |
| Category: | Nonfiction/Science |
| Runtime: | 9.73 |
| Audience: | Adult |
| Language: | English |
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